Preimplantation genetic diagnosis (PGD)
Preimplantation genetic diagnosis of human embryos ( PGD ) is the youngest and most quickly-developing domain of prenatal diagnostics. PGD helps to increase the efficiency of ART for patients who suffer from infertility, and to prevent a hereditary disease in an offspring.
Our clinic has the largest experience of PGD in Russia. In the last 6 years more than 400 IVF cycles with PGD were accomplished.
The most frequent reasons for PGD in our clinic are:
- Chromosomal rearrangements in one of the partners.
- Advanced age of the female partner (above 35 y.o.).
- Three or more miscarriages in early pregnancy.
- More than two unsuccessful IVF/ICSI treatments.
- Severe disorders of spermatogenesis.
Currently the following PGD types are provided in our clinic routinely:
- unbalanced chromosome set in embryos of translocation carriers
- common aneuploidies (chromosomes 13, 16, 18, 22, 23, X, Y)
- Detection of the embryo's genetic sex – sex selection
Fig.3 PGD scheme



