PGD for gender selection
Initially PGD for sex selection was used to avoid sex-linked genetic disease in an offspring, if one of the parents is a carrier. PGD for sex selection may also be performed for family balancing (if, for example, a couple already has a boy and would like to have a girl).
PGD method studies not only sex chromosomes. It can reveal seriouse disease such as Down syndrom. If you plan PGD for family balancing (sex selection), use opportunity to check your future baby for Down syndrom and other chromosome diseases.
The sex of the future baby is determined by the sperm. Some sperms carry a female chromosome (X), and some - a male chromosome (Y). All the eggs carry a female chromosome. According to which sperm has fertilized an egg, a male (genotype 46,XY) or a female organism (genotype 46, XX) is going to develop (see Fig.1).
Fig.1 Sperm + egg (sex determination of the embryo by the sperm)
PGD (preimplantation genetic diagnosis) for sex selection examines an embryo/embryos for male and female chromosomes. To be able to examine an embryo before transferring it into the uterus in vitro fertilization (IVF) is required. The whole process IVF+PGD for sex selection takes 2,5 weeks and consists of several steps (Fig.2):
- Stimulation of ovaries
- Egg collection
- Egg fertilization outside the body
- Embryo culture in incubator
- PGD for sex selection by FISH method
- Transfer into the uterus of embryo of desired sex
- Treatment after the transfer
Fig. 2. PGD for Sex Selection
Ask Question
